Tag: Definitive Screening Design

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The QbD Column: Applying QbD to make analytic methods robust

In our previous blog post, we wrote about using designed experiments to develop analytic methods. This post continues the discussion of analytic methods and shows how a new type of experimental design, the Definitive Screening Design[1] (DSD), can be used to assess and improve analytic methods. We begin with a

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JMP 13 Preview: Making definitive screening designs more accessible

The purpose of screening in designed experiments is “to separate the vital few factors that have a substantial effect on the response from the trivial many that have negligible effects….The definitive screening design can reliably accomplish the task of screening even if there are a couple of second-order effects,” wrote

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Proper and improper use of Definitive Screening Designs (DSDs)

In 2011, my colleague Prof. Chris Nachtsheim and I introduced Definitive Screening Designs (DSDs) with a paper in the Journal of Quality Technology. A year later, I wrote a JMP Blog post describing these designs using correlation cell plots. Since their introduction, DSDs have found applications in areas as diverse

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Eggstra! Eggstra! A new designed eggsperiment

It’s been years since I last dyed Easter eggs, but this year we decided to give it a try. This means I’ve suddenly found the need to hard-boil some eggs. One of my favorite experiments that I’ve blogged about was the eggciting eggsperiment, so it’s the perfect time to revisit

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Bradley Jones leads French design of experiments seminar

The JMP team held a seminar on Sept. 17 in France that focused on design of experiments. Bradley Jones and Peter Goos led this half-day event, and they covered various aspects of design of experiments using four different case studies. They introduced the definitive screening design, which is new in

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Introducing definitive screening designs

In my two previous posts, I introduced the correlation cell plot for design evaluation and then showed how to use the plot to compare designs. Here, I want to use the same plot to show why definitive screening designs are, well, definitive. For a complete technical description of definitive screening